[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 6, Issue 4 (3-2020) ::
2020, 6(4): 272-287 Back to browse issues page
An Agent- based Modeling for Breast Tissue Simulation and the Growth and Spread of Tumor in Various Breast Cancer States
Soheila Mardani , Arash Rahman , Nahid Nafissi
Ph.D. in Computer Engineering, Assistant Professor, Computer Engineering Dept., Faculty of Engineering, Roudehen Branch, Islamic Azad University, Roudehen, Iran
Abstract:   (716 Views)
Introduction: Breast cancer is a cancer that is caused by abnormal growth of breast cells. Modeling  and simulation of the growth and treatment of breast cancer, along with providing the possibility of doing experiments and research, can reduce the time and cost of treatment by predicting some cases. The purpose of the present research was to develop an agent-based model for the simulation of breast tissue and the growth and spread of tumor in various breast cancer states.
Method: In this research, agent-based modeling and simulation method, as well as library studies were used. NetLogo software was used for designing and modeling of breast anatomy and development of model with the required knowledge. Then, according to the patient's age, tumor grading and cancer cells spread, simulation of the growth and development of various breast cancer states in different times were investigated. In order to validate the model, clinical data and reports related to the age and grade, size, growth and spread of tumor in a number of patients with breast cancer were studied and considered and compared with model outcomes.
Results: According to the experiments related to the analysis and validation of the model, the developed model had relatively acceptable results about the growth of breast tumors and the proliferation of cancerous cells in lymph nodes in various breast cancer states. 
Conclusion: Agent-based modeling can be used as a relatively useful and efficient method in identifying and analyzing breast cancer behavior and predicting the growth and proliferation of cancer cells.
Keywords: Agent-based modeling, Breast cancer, Simulation of breast cancer
Full-Text [PDF 1347 kb]   (138 Downloads)    
Type of Study: Original Article | Subject: Artificial Intelligence in Healthcare
Received: 2019/06/30 | Accepted: 2019/08/25
Audio File [MP3 728 KB]  (36 Download)
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mardani S, Rahman A, Nafissi N. An Agent- based Modeling for Breast Tissue Simulation and the Growth and Spread of Tumor in Various Breast Cancer States. Journal of Health and Biomedical Informatics. 2020; 6 (4) :272-287
URL: http://jhbmi.ir/article-1-410-en.html


Volume 6, Issue 4 (3-2020) Back to browse issues page
مجله انفورماتیک سلامت و زیست پزشکی Journal of Health and Biomedical Informatics
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4111